The insulin signaling pathway has been implicated in several physiological and developmental processes.In mammals, it controls expression of 3-Hydroxy-3-Methylglutaryl CoA Reductase (HMGCR), a key enzyme in cholesterol biosynthesis.In insects, which can not synthesize cholesterol de novo, the HMGCR is implicated in the biosynthesis of juvenile horm
The Use of Virtual Surgical Planning for Reduction Cranioplasty
Summary:.Hydrocephalic macrocephaly may occur as a result of untreated hydrocephalus.Reduction cranioplasty is the treatment of choice for these patients when the weight of their head interferes with normal development and negatively impacts quality of life.However, this procedure has several associated risks, including prolonged anesthesia, signif
Exploratory behavior of re-orienting foragers differs from other flight patterns of honeybees.
Honeybees, Apis mellifera, perform re-orientation flights to learn about the new surroundings of the hive when their hive is transported to a new location.Since the pattern of re-orientation flights has not yet been studied, we asked whether this form of exploratory behavior differs from the well described exploratory orientation flights performed
Study of the radioprotective properties of fumaric acid and 3-hydroxypyridine fumarate under the action of ionizing radiation on human cells
In the modern world, such a situation has developed that the development of nuclear energy and the use of sources of ionizing radiation in various fields of activity have created a potential threat of radiation hazard to humans.In this connection, the actual direction is the study of ways to increase the radioresistance of human cells and tissues t